GLP-1 receptor agonists — the class of medications that includes Ozempic (semaglutide) and Mounjaro (tirzepatide) — have transformed the treatment of obesity and excess weight worldwide. In South Africa, access to these medications is legal, straightforward, and increasingly available online. But many patients still don't know where to start.
This guide walks you through exactly how to get a GLP-1 prescription in South Africa — who qualifies, what the consultation involves, and what happens after you receive your script.
Quick answer: In South Africa, you need a valid prescription from an HPCSA-registered medical doctor to obtain Ozempic or Mounjaro. You do not need a specialist. The process can be done entirely online and typically takes 24–48 hours from initial enquiry to receiving your prescription.
GLP-1 (glucagon-like peptide-1) receptor agonists work by mimicking a naturally occurring gut hormone that regulates appetite and blood sugar. They tell your brain you're full, slow gastric emptying, and reduce cravings — particularly for high-calorie foods.
The medications available in South Africa for weight management include:
GLP-1 therapy is a medical treatment — not a lifestyle supplement. Your doctor will assess you against established clinical criteria before prescribing:
You are generally not a suitable candidate if you have:
Your doctor will review all of this during the consultation. If you are unsure whether you qualify, it costs nothing to complete our intake form and book — the consultation is the right place to find out.
Provide your basic health information — height, weight, relevant medical history, current medications, and reason for seeking treatment. This allows the doctor to prepare for your consultation and identify any contraindications in advance.
The R700 fee covers your telehealth consultation (R350) and your first GLP-1 prescription (R350) — everything is included for your first visit. No hidden fees. Medication costs are separate and purchased at a pharmacy of your choice.
You'll meet with a HPCSA-registered medical doctor via video call. The doctor will review your intake form, ask follow-up questions, discuss your goals, and determine whether GLP-1 therapy is appropriate for you. They'll recommend a specific medication and starting dose.
If the doctor confirms you are a suitable candidate, you'll receive an electronic prescription (e-script) via email typically within hours of the consultation. This is a valid, legal prescription accepted at any South African pharmacy.
Take your e-prescription to any registered pharmacy in South Africa — Dis-Chem, Clicks, independent pharmacies, or a pharmacy with delivery. Ask the pharmacist to check stock, as Ozempic and Mounjaro can sometimes have limited availability. Your pharmacist can also counsel you on the injection technique.
GLP-1 therapy is a progressive treatment — doses are increased gradually over several months. Every 4 weeks, you'll have a brief check-in with the doctor to review your progress, manage any side effects, and renew your prescription. Renewals are R350.
Present your e-prescription at the pharmacy counter. The pharmacist will dispense the medication, show you the injection pen, and explain how to use it. Ozempic and Mounjaro are both pre-filled injection pens used once a week — they are injected subcutaneously (under the skin) in the abdomen, thigh, or upper arm.
Neither medication requires refrigeration once the pen is in use (though it should be stored in the fridge before opening). The pharmacist will give you full storage and handling instructions.
| Medication | Approximate Monthly Cost | Injection Frequency |
|---|---|---|
| Ozempic (semaglutide) | R1,500 – R2,800 | Once weekly |
| Mounjaro (tirzepatide) | R2,500 – R4,500 | Once weekly |
| Saxenda (liraglutide) | R2,000 – R3,500 | Daily |
Prices vary by pharmacy and dose strength. Most medical aids in South Africa do not cover these medications for weight management — they are typically paid out of pocket. See our guide on medical aid coverage for GLP-1 in South Africa.
Yes, absolutely. The HPCSA (Health Professions Council of South Africa) permits telehealth consultations under Booklet 10 of their ethical guidelines. Provided the doctor conducts a proper clinical assessment — which includes reviewing your medical history and conducting a video consultation — issuing a prescription via telehealth is legal and ethical.
Every prescription issued by Metabolic Doc comes from a HPCSA-registered medical doctor. Our e-prescriptions are valid at any registered pharmacy in South Africa.
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